Endocrine Abstracts

Growth hormon (GH) counteracts the effects of insulin on glucose metabolism and GH excess may lead to insulin resistance (IR). Impaired glucose tolerance (IGT) and diabetes mellitus (DM) are frequently associated with acromegaly. Microalbuminuria (MAU) is a well established cardiovascular (CV) risk factor and a predictor of CV mortality in both diabetic and nondiabetic subjects.The aim of this preliminary study was to investigate the MAU levels as a mark...

Generously supported by IPSEN)-->Acromegaly is a chronic disease with an important impact on patients, health-related quality of life (HRQoL). Acromegaly quality of life questionnaire (AcroQoL) is a disease-generated QoL questionnaire comprising 22 questions each having five possible responses scored 1–5, the maximum score of 110 reflecting best possible QOL, and quoted as a percentage. The 22 items break down into two categorie...

Cardiovascular diasease (CV) is the leading cause of mortality in acromegalic patients. Although acromegalic cardiomyopathy has been extensively investigated, there is a lack of data about atherosclerosis in acromegaly.We aimed to the evaluate the extent of carotid atherosclerosis with various CV biomarkers in acromegaly. Sixty-one acromegalic patients and 21 age and sex matched healthy controls were included. We measured carotid intima media thickness (...